# Specialty amines and ethanolamines: Regulation

Flammable, corrosive and sometimes sensitising: the hazards

Source page: https://www.materialinsights.org/chemicals/specialty_amines/regulation/

What this tab covers How it is regulated and what could disrupt supply: hazard classification, rules in the EU, US and India, anti-dumping duties and other trade measures, and supply-risk notes.

#### Hazards

| Classification | UN number | Key risks |
|---|---|---|
| flammable gas or liquid (methylamines, ethylamines); skin corrosion cat 1 (most amines); acute toxicity; EDA respiratory sensitiser | UN1061, UN1032, UN1235, UN2491, UN1604 | Corrosive and flammable; secondary amines can form carcinogenic nitrosamines, a concern for drug impurities and for amine-based carbon capture emissions. |

#### Main rules

| Where | Rule | Effect |
|---|---|---|
| **EU** | REACH restriction on DMF (from 12 Dec 2023) and NMP (from 2020) | cuts use of amine-derived solvents unless exposure limits are met |
| **US and EU** | Regulator limits on nitrosamine impurities in drugs (from 2018 onwards) | tighter purity specs for amines used in APIs |
| **Global** | Chemical Weapons Convention schedules for some ethanolamines (TEA, MDEA) | export reporting for triethanolamine and N-methyldiethanolamine |

#### India

| Rule | Effect |
|---|---|
| **MSIHC Rules 1989 (methylamine listed as hazardous)** | safety reporting and storage limits |
| **Petroleum and Explosives Safety Organisation (PESO) rules for pressurised gas storage** | licensing for anhydrous amine tanks |
| **Chemical Weapons Convention Act 2000 reporting for scheduled chemicals such as TEA** | export and production declarations |

#### Trade measures

- No current anti-dumping duty on major amines was found in the sources used (check DGTR)

#### Supply risk

Moderate. Products are made by few producers each, and India depends on imported methanol, ammonia and ethanolamines that pass through the Gulf. Not on critical lists.

## Other sections

- [Summary](https://www.materialinsights.org/chemicals/specialty_amines/index.md)
- [Overview](https://www.materialinsights.org/chemicals/specialty_amines/overview/index.md)
- [Correlation](https://www.materialinsights.org/chemicals/specialty_amines/correlation/index.md)
- [Production route](https://www.materialinsights.org/chemicals/specialty_amines/routes/index.md)
- [Production](https://www.materialinsights.org/chemicals/specialty_amines/production/index.md)
- [Feedstocks](https://www.materialinsights.org/chemicals/specialty_amines/feedstocks/index.md)
- [Cycles](https://www.materialinsights.org/chemicals/specialty_amines/cycles/index.md)
- [Trading](https://www.materialinsights.org/chemicals/specialty_amines/trading/index.md)
- [Movement](https://www.materialinsights.org/chemicals/specialty_amines/movement/index.md)
- [Characteristics](https://www.materialinsights.org/chemicals/specialty_amines/characteristics/index.md)
- [Emissions](https://www.materialinsights.org/chemicals/specialty_amines/emissions/index.md)
- [Relationships](https://www.materialinsights.org/chemicals/specialty_amines/links/index.md)