Material Insights · Understanding the Material World

Reagents and high-purity lab chemicals: Feedstocks

Why a by-product shortage like acetonitrile can still bite

What this tab covers What it is made from and what it feeds: the raw materials and energy per tonne with their share of cost (linked to the commodity table), who is low-cost and why, and the chemicals made from it.

Reagents start from ordinary commodity chemicals; feedstock is a small part of the price. What decides competitiveness is purification know-how, quality systems, certification, packaging and access to lab customers. Shortages of a by-product, such as acetonitrile, can still disrupt the business.

Inputs per tonne

InputQuantity per tonneRoleShare of costSource
Technical acids and bases (sulphuric, hydrochloric, nitric acid; caustic soda)about 1.1-1.5 t per t reagent (indicative)starting material for analytical gradesunder 10% of reagent price (indicative)indicative
Technical solvents (methanol, acetonitrile, hexane)about 1.1-1.3 t per t (indicative)HPLC and LC-MS solventsabout 10-30% for solvents (indicative)indicative
Oil Crude oilindirectsolvent feedsmallindicative
Qz Silica sandpackagingglass packagingpackaging can be a large share for small packs (indicative)indicative
Biological feedstocks (sugars, media, cell lines)not meaningfulenzymes and biochemicalssmallindicative

Who is low-cost, and why

Global leaders win on catalogue breadth, quality systems and distribution, not on cost. Indian and Chinese makers are cheaper in standard laboratory and analytical grades.